Sibutramine is a derivative of fluoxetine. Apart from having a mild thermogenic action, it is also a proven central appetite suppressant. Sibutramine is capable of acting as a Selective Serotonin Reuptake Inhibitor (SSRI) and Selective Norepinephrine Reuptake Inhibitor (SNRI). In simple words, this means that Sibutramine works by acting on the area in your brain that is responsible for controlling hunger and providing you with a sense of fullness and satisfaction.
Sibutramine has been shown to produce 50-100% additional weight loss above that identified with significant lifestyle changes. Obesity related medical conditions such as Type 2 Diabetes, hypertension and sleep apnea are also believed to reduce in proportion to the weight lost. Also studies have shown that Sibutramine has a specific effect of raising HDL levels quite markedly.
Sibutramine should not be used if you have certain medical conditions. Before using this medicine, consult your doctor if you have: eating disorders (e.g., anorexia nervosa, bulimia nervosa), uncontrolled or poorly controlled high blood pressure, severe heart disease (coronary artery disease, history of heart attack, congestive heart failure, abnormal heart rhythms), and stroke. Also, Sibutramine should not be used with certain other weight loss medicines like diethylpropion and phentermine, since very serious interactions may occur.
When on Sibutramine, do not consume large amounts of beverages that contain caffeine (coffee, tea, colas, energy drinks like red bull, battery etc), since side effects like increased heart rate can get aggravated.
Please note that this posting does not include all possible interactions. Therefore, before using Sibutramine, inform your doctor about all the medications you are taking.
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